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Homeotic selector genes code for DNA binding
proteins (transcription factor) -transcriptiefactor:
• homeodomain
(protein)
• homeobox (DNA)
• interaction with DNA and with other
regulatory proteins
• helix-turn-helix DNA binding motif
• 60
amino acids domain
• HOX genes are a subgroup of homeobox
genes
*Order of sequence matches the spatial order of
expression
-HOX complex: chromosome region with hox
genes
