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Transcriptional Therapeutics involves the clinical delivery, integration and regulation of engineered DNA molecules (exogenous gene programs) as a method for expressing specific modulator proteins. Our R&D efforts are focused on achieving a high degree of specificity and control of cellular and sub-cellular interactions using combinations of special-function DNA modules. Success in doing so will provide clinicians with powerful new tools to fight complex, multi-variant diseases, while minimizing toxic effects. The combination of Intrexon and RheoGene creates an advanced research and development biotechnology enterprise that is expected to establish a leading position in gene-based therapeutics.